Who We Are
Luciole is a start-up company focusing on the discovery and development of small molecules that accelerate the repair of oxidative damage to mitochondrial DNA (mtDNA). The company has combined decades of expertise in mitochondrial function, drug discovery and development, and use of the virtual company model to become the leader in correcting oxidative damage to mtDNA.
Luciole is applying cutting edge science to enhance the functionality of OGG1 (8-oxoguanine DNA glycosylase), the key enzyme in the initiation of base excision repair (BER) of mtDNA.
Eric Morrel, PhD
Vice President and COO, Director, Co-founder
Professor, Molecular and Medical Genetics, School of Medicine, Oregon Health and Science University
Professor, Molecular and Medical Genetics, School of Medicine,
Oregon Health and Science University
Page and William Black Professor of Neurology
Chief, Division of Movement Disorders
Columbia University Irving Medical Center
Associate Professor of Medicine
University of Pittsburgh
Ralph A. Rivero, PhD
Professor of Medicine, University of Minnesota